8-chloro-6-hydroxy-4,4-dimethyl-4H-3,1-benzoxazin-2-one → 8-Chloro-6-(4-phenylsulfinyl-butoxy)-4,4-dimethyl-4H-3,1-benzoxazin-2-one

HRID 463251Notes

Reaction equation

[Cl:1][C:2]1[C:11]2[NH:10][C:9](=[O:12])[O:8][C:7]([CH3:14])([CH3:13])[C:6]=2[CH:5]=[C:4]([OH:15])[CH:3]=1.[C:16]1([S:22]([CH2:24][CH2:25][CH2:26][CH2:27]Br)=[O:23])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[Cl:1][C:2]1[C:11]2[NH:10][C:9](=[O:12])[O:8][C:7]([CH3:13])([CH3:14])[C:6]=2[CH:5]=[C:4]([O:15][CH2:27][CH2:26][CH2:25][CH2:24][S:22]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[O:23])[CH:3]=1

Participants

Reactant 2

HCID 202816978-chloro-6-hydroxy-4,4-dimethyl-4H-3,1-benzoxazin-2-one

HCID 545301224-Phenylsulfinylbutylbromide

Product 1

HCID 202817398-Chloro-6-(4-phenylsulfinyl-butoxy)-4,4-dimethyl-4H-3,1-benzoxazin-2-one

Procedure

Prepared analogously to Example 4 from 8-chloro-6-hydroxy-4,4-dimethyl-4H-3,1-benzoxazin-2-one and 4-phenylsulfinyl-butylbromide.

Sources & evidence

ORD record: ord-0ecff234ae144c5ea57ff79dac691113
Source dataset: uspto-grants-1985_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04518597

Reaction notes

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