6-hydroxy-4,4,7-trimethyl-4H-3,1-benzoxazin-2-one → 6-[4-(4-acetamido-phenylmercapto)-butoxy]-4,4,7-trimethyl-4H-3,1-benzoxazin-2-one

HRID 463272Notes

Reaction equation

HRID 463272 reaction equation
[OH:1][C:2]1[C:3]([CH3:15])=[CH:4][C:5]2[NH:10][C:9](=[O:11])[O:8][C:7]([CH3:13])([CH3:12])[C:6]=2[CH:14]=1.[C:16]([NH:19][C:20]1[CH:25]=[CH:24][C:23]([S:26][CH2:27][CH2:28][CH2:29][CH2:30]CS([O-])(=O)=O)=[CH:22][CH:21]=1)(=[O:18])[CH3:17]>>[C:16]([NH:19][C:20]1[CH:25]=[CH:24][C:23]([S:26][CH2:27][CH2:28][CH2:29][CH2:30][O:1][C:2]2[C:3]([CH3:15])=[CH:4][C:5]3[NH:10][C:9](=[O:11])[O:8][C:7]([CH3:12])([CH3:13])[C:6]=3[CH:14]=2)=[CH:22][CH:21]=1)(=[O:18])[CH3:17]

Participants

3

Reactant 2

HCID 202816846-hydroxy-4,4,7-trimethyl-4H-3,1-benzoxazin-2-oneHCID 1317142264-(4-Acetamidophenylmercapto)-butylmesylate

Product 1

HCID 202817756-[4-(4-acetamido-phenylmercapto)-butoxy]-4,4,7-trimethyl-4H-3,1-benzoxazin-2-one

Procedure

Prepared analogously to Example 4 from 6-hydroxy-4,4,7-trimethyl-4H-3,1-benzoxazin-2-one and 4-(4-acetamidophenylmercapto)-butylmesylate.

Sources & evidence

ORD record
ord-e745ae8f3f034486bc4c6cc9be5ac781
Source dataset
uspto-grants-1985_05
Patent number
US04518597

Reaction notes

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