Toluene → HCID 20283195, compound

Participants

Reaction Conditions

Reaction Steps

11.5 g of p-trifluoromethoxyphenyl isocyanate are dissolved in 10 ml of toluene and are mixed at 25° C. with 10 ml of a 0.02 molar solution of potassium acetate/18-Crown-6 (1:1) in butyl acetate. After the reaction mixture has heated itself to 30° C., 5.0 g of phenyl isocyanate are added over a period of 5 minutes and the mixture is stirred until all the isocyanate has reacted. After separating by column chromatography, the two mixed isocyanurates 1,3-(di-p-trifluoromethoxyphenyl)-5-phenyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione and 3,5-diphenyl-1-(p-trifluoromethoxyphenyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione are obtained in a 73% yield.

Provenance & Evidence