2-Iodo-4-(trifluoromethyl)phenol → 3-cyano-N-(2,4-dimethoxybenzyl)-4-[2-iodo-4-(trifluoromethyl)phenoxy]-N-1,2,4-thiadiazol-5-ylbenzenesulfonamide

Participants

Role	Name	HCID	Charge
Reactant	2-Iodo-4-(trifluoromethyl)phenol	HCID 11572816	—
Reactant	3-cyano-N-(2,4-dimethoxybenzyl)-4-fluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide	HCID 58042254	—
Product	3-cyano-N-(2,4-dimethoxybenzyl)-4-[2-iodo-4-(trifluoromethyl)phenoxy]-N-1,2,4-thiadiazol-5-ylbenzenesulfonamide	HCID 59436485	—

Reaction Steps

Prepared according to Method O (below) at room temperature using 3-cyano-N-(2,4-dimethoxybenzyl)-4-fluoro-N-1,2,4-thiadiazol-5-ylbenzenesulfonamide (Preparation 68) and 2-iodo-4-(trifluoromethyl)phenol (Preparation 224). The title compound was isolated as a white solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08541588B2
Source dataset	uspto-grants-2013_09
ORD ID	ord-65964556440d4f1c9e38432b8003beb8
Source note	uspto-grants-2013_09