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HRID463428

反应详情

EQUATION

反应方程式

HRID 463428 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)OC(C)=O
HCID7918

Acetic anhydride

C4H6O3

结构：CC(=O)[O-].[Na+]
HCID517045

Sodium Acetate

C2H3NaO2

结构：CCOC(CBr)(OCC)C(=NOC)C(=O)NC1C(=O)N2C(C(=O)O)C(O)CS[C@H]12
HCID86738093

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(CBr)(OCC)C(=NOC)C(=O)NC1C(=O)N2C(C(=O)O)=CCS[C@H]12
HCID131712534

未命名化合物

收率 69.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(=O)CC(C)C
溶剂HCID7909

4-Methyl-2-pentanone

C6H12O

PROCEDURE

实验过程

7-(2-Methoxyimino-3,3-diethoxy-4-bromobutyramido)-3-hydroxycepham-4-carboxylic acid (syn isomer, 5 g), acetic anhydride (4.55 ml), sodium acetate (1.45 g), and methyl isobutyl keton (50 ml) were treated in a similar manner to that of Example 43 to give 7-(2-methoxyimino-3,3-diethoxy-4-bromobutyramido)-3-cephem-4-carboxylic acid (syn isomer, 3.36 g).