Sodium borohydride → HCID 20280921, compound

Participants

Reaction Steps

Into a 250 cc reaction flash equipped with stirrer, thermometer, reflux condensor and heating mantle is placed 28.7 grams (0.13 moles) of the reaction product of Example III containing the compounds having the structures: ##STR86## 9.6 grams (0.26 moles) of sodium borohydride and 50 ml of anhydrous isopropanol. The isopropanol and sodium borohydride are first mixed together and placed in the flask. The resulting composition is heated to reflux and then over a period of one hour the isopropoxinene norbornane propanal is added. The resulting reaction mass is refluxed for a period of three hours. The reaction mass is then washed to neutral and distilled on a micro vigreux column yielding the following fractions:

Provenance & Evidence