反应详情

An acetone solution of 6.5 g (0.032M) of the potassium salt of 2-mercapto-1-methyl-benzimidazole and 9.7 g (0.045M) of α-bromophenylacetic acid is stirred at room temperature overnight. The solid which is collected is washed with water and the filtrate is concentrated to remove the solvent. The combined materials are recrystallized from acetonitrile. The recrystallized material weighs 8.3 g (87% yield) and melts at 157°-9° C.

1. customThe solid which is collected
2. washis washed with water
3. concentrationthe filtrate is concentrated
4. customto remove the solvent
5. customThe combined materials are recrystallized from acetonitrile