ethyl P-methyl-2-nitro-5-chlorophenylphosphinate → ethyl P-methyl-2-amino-5-chlorophenylphosphinate

Participants

Reaction Steps

Ethyl P-methyl-2-nitro-5-chlorophenylphosphinate (1.7 g, 7.5 mmol) dissolved in methanol (25 ml) is added to 200 mg of 5% palladium on carbon. The mixture is hydrogenated at 32 psi for 1 hour. The catalyst is then filtered off and the filtrate is evaporated to dryness to give ethyl P-methyl-2-amino-5-chlorophenylphosphinate.

Provenance & Evidence