Chloroform → HCID 54471596, compound

Participants

Reaction Steps

To iodobenzene diacetate (3.9 g, 12 mmol) in 100 ml of acetone is added at RT 2-nitro-5-(3,5-dichloro-2-pyridyloxy)aniline (3.0 g, 10 mmol), neat, in portions over 10 minutes. The reaction is stirred at RT overnight and is then stripped. Chloroform is added to the residue, and this mixture is filtered through celite. The filtrate is washed with water (2X) and with brine, dried over sodium sulfate and stripped to give 5-(3,5-dichloro-2-pyridyloxy)benzo-2,1,3-oxadiazole N-oxide. (D; X=H, Y=Cl, Z=Cl).

Provenance & Evidence