Methoxyacetyl chloride → HCID 13193372, compound

Participants

Reaction Steps

6.0 g (29.5 millimoles) of 6-(p-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone and 3.9 g (35.9 millimoles) of methoxyacetyl chloride in 150 ml of absolute tetrahydrofuran were refluxed for 2 hours, while stirring. The product was filtered off under suction at 10° C., washed with water and recrystallized from dimethylformamide/water. 3.6 g (44%) of 6-[p-(methoxyacetylamino)-phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone were obtained as colorless crystals. Mp.: 212° C.

Provenance & Evidence