HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxypropanoyl chloride → HCID 13193371, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxypropanoyl chloride | HCID 92495 | — |
| Reactant | 6-(4-Aminophenyl)-4,5-dihydropyridazin-3(2H)-one | HCID 676750 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 13193371 | HCID 13193371 | 76% |
Reaction Steps
20.3 g (107 millimoles) of 6-(p-aminophenyl)-4,5-dihydro-3(2H)-pyridazinone were stirred with 14.7 g (0.12 mole) of 2-methoxypropionyl chloride and 400 ml of absolute acetone for 10 hours at room temperature. The product was filtered off under suction at 10° C., washed with cold acetone and dried at 70° C. under reduced pressure. 20.8 g (76%) of 6-[p-(2-methoxypropionylamino)-phenyl]4,5-dihydro-3(2H)-pyridazinone were obtained. Mp.: 245°-247° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04544562 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-5c474fffba4442f09a27b56102e51102 |
| Source note | uspto-grants-1985_10 |