反应详情

1.0 g of 9-chloroacridine, 0.926 g of 2-hydrazino-2-thiazoline hydrobromide and 0.767 g of anhydrous sodium acetate are dissolved in 100 ml of dry ethanol, heated to boiling under reflux for 2 hours and the red solution is then evaporated in vacuo. The residue is treated with water and the crystalline mass is filtered under suction. After recrystallization from ethanol, there is obtained 9-acridanone (2-thiazolidinylidene)hydrazone of melting point 212°-216° (decomposition).

1. temperatureheated
2. temperatureunder reflux for 2 hours
3. customthe red solution is then evaporated in vacuo
4. additionThe residue is treated with water
5. filtrationthe crystalline mass is filtered under suction
6. customAfter recrystallization from ethanol