HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 5-(Dimethyl)aminobenzo[b]furan
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | 1-Benzofuran-5-amine | HCID 1477152 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 5-(Dimethyl)aminobenzo[b]furan | HCID 20265057 | — |
Reaction Steps
To a stirred solution of 5-aminobenzo[b]furan in CH3CN is added 37% aqueous formaldehyde followed by sodium cyanoborohydride and glacial acetic acid to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04544667 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-ead88befcd864447a158e6b20cf5f5fe |
| Source note | uspto-grants-1985_10 |