反应详情

A solution of 20% thionyl chloride in toluene is added dropwise to a magnetically stirred, warmed mixture of 2,6-dichlorocinnamic acid (20.74 g) in toluene (119 ml) and the mixture brought to reflux for 6 hrs after it clears to a yellow haze. The reaction mixture is cooled overnight, filtered and concentrated in vacuo to afford a pale yellow solid, M.P. 64.5°-66° C.

1. temperaturewarmed
2. temperatureto reflux for 6 hrs after it
3. temperatureThe reaction mixture is cooled overnight
4. filtrationfiltered
5. concentrationconcentrated in vacuo
6. customto afford a pale yellow solid, M.P. 64.5°-66° C.