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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 463812Generated: October 25, 2026

Ethanolamine → Phenylglycine nitrile

https://huagongshe.com/reaction/463812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
ReactantHCID 20265457HCID 20265457—
ProductPhenylglycine nitrileHCID 76307—

Reaction Conditions

Temperature20 °C

Reaction Steps

100 g of 2-cyanomethyl-N-phenylphthalimide were introduced, a little at a time, into 100 g of monoethanolamine at 80° C. After 10 minutes, the mixture was cooled to 20° C., and 400 g of ice water were added dropwise. The precipitated product was filtered off under suction and washed neutral with ice water.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04544755
Source datasetuspto-grants-1985_10
ORD IDord-7c7b2faa11fd4a8da8c7465902762202
Source noteuspto-grants-1985_10