HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → Methyl 2-methoxyimino-2-(3-chloro-4-hydroxyphenyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | 2-Methoxyimino-2-(3-chloro-4-hydroxyphenyl)acetic acid | HCID 136093950 | — |
| Product | Methyl 2-methoxyimino-2-(3-chloro-4-hydroxyphenyl)acetate | HCID 136176295 | — |
Reaction Steps
2-Methoxyimino-2-(3-chloro-4-hydroxyphenyl)acetic acid (a mixture of syn and anti isomers) (7 g.) and diazomethane (1.5 g.) were reacted and the product was purified by column chromatography according to a similar manner to that of Preparation (5-3)(b) to give crystals of methyl 2-methoxyimino-2-(3-chloro-4-hydroxyphenyl)acetate (syn isomer) (3.0 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04544653 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-9ed1ecce962c4f84826cfacfe4c9868e |
| Source note | uspto-grants-1985_10 |