Acetohydrazide → HCID 53711504, compound

HRID 463918Notes

Reaction equation

HRID 463918 reaction equation
[CH3:1][O:2][N:3]=[C:4]([C:10]([CH3:12])=O)[C:5]([O:7][CH2:8][CH3:9])=[O:6].[C:13]([NH:16][NH2:17])(=[O:15])[CH3:14]>C(O)C>[CH3:1][O:2][N:3]=[C:4]([C:10](=[N:17][NH:16][C:13](=[O:15])[CH3:14])[CH3:12])[C:5]([O:7][CH2:8][CH3:9])=[O:6]

Participants

4

Reactant 2

HCID 14039AcetohydrazideHCID 43493Ethyl (2Z)-2-methoxyimino-3-oxo-butanoate

Product 1

HCID 53711504HCID 53711504, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of ethyl 2-methoxyiminoacetoacetate (a mixture of syn and anti isomer) (226.6 g.) and acetohydrazide (78.5 g.) in ethanol (500 ml.) was stirred for 1.5 hours at ambient temperature. Precipitates were collected by filtration, washed with ethanol and ether and dried to give ethyl 2-methoxyimino-3-acetylhydrazonobutyrate (a mixture of syn and anti isomers) (155.7 g.), mp 190° to 191.5° C.

Workup

  1. customPrecipitates
  2. filtrationwere collected by filtration
  3. washwashed with ethanol and ether
  4. customdried

Sources & evidence

ORD record
ord-fc9ac21f0e464c8184898957fe1a5ba6
Source dataset
uspto-grants-1985_10
Patent number
US04544751

Reaction notes

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