Hydroxylamine, O-ethyl- → HCID 178449928, compound

HRID 463950Notes

Reaction equation

HRID 463950 reaction equation
[C:1]([CH:6]1[C:11](=[O:12])[CH2:10][CH:9]([C:13]2[C:14](=[O:23])[NH:15][C:16]3[C:21]([CH:22]=2)=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:8][C:7]1=[O:24])(=O)[CH2:2][CH2:3][CH3:4].[CH2:25]([O:27][NH2:28])[CH3:26]>CO>[CH2:25]([O:27][NH:28][C:1](=[C:6]1[C:11](=[O:12])[CH2:10][CH:9]([C:13]2[C:14](=[O:23])[NH:15][C:16]3[C:21]([CH:22]=2)=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:8][C:7]1=[O:24])[CH2:2][CH2:3][CH3:4])[CH3:26]

Participants

4

Reactant 2

HCID 69357Hydroxylamine, O-ethyl-HCID 20263431HCID 20263431, compound

Product 1

HCID 178449928HCID 178449928, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

10 parts by weight of 2-butyryl-5-(2-oxoquinol-3-yl)-cyclohexane-1,3-dione, 2.0 parts by weight of ethoxyamine and 100 parts of methanol were stirred for 8 hours at room temperature. The solvent was distilled off under reduced pressure, the residue was taken up in 200 parts of dichloromethane, and the solution was washed with 5% strength hydrochloric acid, dried over sodium sulfate and evaporated down under reduced pressure. 2-(1-Ethoxyaminobutylidene)-5-(2-oxoquinol-3-yl)-cyclohexane-1,3-dione of melting point 155°-157° C. was obtained (active ingredient No. 2).

Workup

  1. distillationThe solvent was distilled off under reduced pressure
  2. washthe solution was washed with 5% strength hydrochloric acid
  3. dry with materialdried over sodium sulfate
  4. customevaporated down under reduced pressure

Sources & evidence

ORD record
ord-13c6cdb5376c49a5a37035f69c1a3e1a
Source dataset
uspto-grants-1985_10
Patent number
US04545806

Reaction notes

Loading…