反应详情

4.0 grams (0.0146 mole) of 4-cyano-5,6-diphenyl-3-(2H)-pyridazinone was dissolved in 40 mls of pyridine along with 10 mls of distilled water. 2 mls of acrylonitrile was added into this solution and the mixture heated to reflux for 2 hours. The solution was cooled and the solvent distilled at reduced pressure. The residual solid was recrystallized from ethyl alcohol to give 2 grams (42%) yield of a white solid which melted at 160°-161° C. The infrared spectrum showed the C-C band at 3.3μ, the nitrile group at 4.5μ, and the carboxy groups for an amide at 6.0μ.

1. temperaturethe mixture heated
2. temperatureto reflux for 2 hours
3. temperatureThe solution was cooled
4. distillationthe solvent distilled at reduced pressure
5. customThe residual solid was recrystallized from ethyl alcohol
6. customto give 2 grams (42%) yield of a white solid which melted at 160°-161° C