反应详情

8.0 grams (0.0175 mole) of the product of Example 1 was reacted with 2.1 grams of ethyl-vinyl sulfone in 60 mls of pyridine. This solution was heated on a steam bath for 2 hours, cooled and the solvent distilled at reduced pressure. The residual oil was taken up in ethyl alcohol. 5.0 grams (72% yield) of a solid precipitated and was filtered, washed with petroleum ether and air dried. The infrared spectrum showed the nitrile band at 4.5μ, the carbonyl band at 6.0μ, the SO2 band at 8.7μ.

1. temperatureThis solution was heated on a steam bath for 2 hours
2. temperaturecooled
3. distillationthe solvent distilled at reduced pressure