Ethanolamine → HCID 13293005, compound

Participants

Reaction Steps

In the same manner as in Example 4-(1), 7-bromo-9(S)-acetoxyacetyl-6,9,11-trihydroxy-5,7,8,9,10,12-hexahydronaphthacene-5,12-dione (200 mg) obtained in Reference Example 4 was treated with ethanolamine (30 mg) and the reaction product was post-treated to give dark reddish brown crystals of 7(S)-β-hydroxyethylamino-9(S)-acetoxyacetyl-6,9,11-trihydroxy-5,7,8,9,10,12-hexahydronaphthacene-5,12-dione. M.P., 100°-103° C. [α]D20 =+166.2° (c=0.1, CHCl3).

Provenance & Evidence