Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nitric Acid → 4-Methyl-3-nitrobenzonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nitric Acid | HCID 944 | — |
| 반응물 | p-Tolunitrile | HCID 7724 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | 4-Methyl-3-nitrobenzonitrile | HCID 589333 | — |
반응 단계
With stirring, concentrated H2SO4 (205 ml) was cooled to 5° C. Keeping the temperature below 20° C., concentrated HNO3 (85 ml) was added dropwise. Keeping the temperature below 40° C., p-tolunitrile (96 ml) was then added dropwise. After stirring 10 minutes, the reaction mixture was quenched onto 3 kilograms ice, granulated and filtered to yield title product: 120.5 g; m.p. 102°-104°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04546113 |
| 출처 데이터셋 | uspto-grants-1985_10 |
| ORD ID | ord-dea54de7906347e2b8dfc789459cd8c0 |
| 출처 메모 | uspto-grants-1985_10 |