(Phenylmethyl)hydrazine → 5-amino-1-benzyl-1H-pyrazole-4-carbonitrile

Participants

Reaction Steps

A procedure analogous to that described in Example 1 was followed except 1.55 g (12.7 mM) of ethoxymethylene malononitrile was added to 1.70 g (13.9 mM) of benzylhydrazine in ethanol. Following completion of the reaction 0.82 g (33%) of the product was obtained as a tan solid; tlc, Rf =0.24, silica gel, ethyl acetate:hexane (1:1).

Provenance & Evidence