反应详情

温度

20 °C

The pH is adjusted to 7 at 20° C. and 3 ml of `Arquad 16-29` is added followed by a further 2.2 equivalents of caustic soda and 23 g of 1-amino-1-cyanocyclohexane over 20 minutes with cooling to maintain a temperature of 20° C. The reaction is stirred for a further five minutes and filtered, washed and dried to yield 36.7 g of the title compound, as a white solid (89%).

1. customis adjusted to 7 at 20° C.
2. temperaturewith cooling
3. filtrationfiltered
4. washwashed
5. customdried