Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 13533681, compound

HRID 464143Notes

Reaction equation

HRID 464143 reaction equation
[CH3:1][N:2]([CH3:24])[CH2:3][CH2:4][CH2:5][N:6]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([N+:15]([O-])=O)[CH:13]=2)[C:8]2[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][C:7]1=2.C1(N)C(F)=C(F)C(F)=C(N)C=1F.Cl.Cl>>[NH2:15][C:12]1[CH:13]=[C:14]2[C:9]([C:8]3[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][C:7]=3[N:6]2[CH2:5][CH2:4][CH2:3][N:2]([CH3:24])[CH3:1])=[CH:10][CH:11]=1

Participants

3

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 13533674HCID 13533674, compound

Product 1

HCID 13533681HCID 13533681, compound

Procedure

3-Amino-6,7,8,9,10,11-hexahydro-N,N-dimethyl-5H-cyclooct[b]indole-5-propanamine was prepared following the procedure of Example 1, using 6,7,8,9,10,11-hexahydro-N,N-dimethyl-3-nitro-5H-cyclooct[b]indole-5-propanamine instead of 6,7,8,9,10,11-hexahydro-N,N-dimethyl-1-nitro-5H-cyclooct[b]indole-5-propanamine and was converted to the dihydrochloride salt; m.p. 235°-238° C.

Sources & evidence

ORD record
ord-abb3a8269bfa4c7586adeeef9e604e15
Source dataset
uspto-grants-1985_10
Patent number
US04546193

Reaction notes

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