Isopropylamine → HCID 13385716, compound

Participants

Reaction Steps

Isopropylamine (1.77 g., 0.03 mole) was added to a solution of 4-chloro-1-ethyl-[1,2,4]triazolo-[4,3-a]quinoxaline (2.3 g., 0.01 mole), the product of Example 4, in N,N-dimethylformamide (30 ml.). Within 30 minutes, a precipitate formed. The reaction mixture was then stirred overnight at room temperature. The precipitate was separated by filtration and washed with N,N-dimethylformamide. Recrystallization from ethanol then gave 1.6 g. (63% yield) of 4-isopropylamino-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxaline, m.p. 222°->4° C. Mass spectrum: m/e, 255 (P).

Provenance & Evidence