HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 70413153, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 5-((6-Methyl-3-pyridyl)methyl)-2-(nitroamino)-1H-pyrimidin-4-one | HCID 3018360 | — |
| Reactant | N-(3-Aminopropyl)-N-methylpyridin-2-amine | HCID 20262876 | — |
| Product | HCID 70413153 | HCID 70413153 | — |
Reaction Steps
2-[N-(3-aminopropyl)-N-methylamino]pyridine (1.33 g) and 2-nitroamino-5-(6-methylpyrid-3-ylmethyl)pyrimid-4-one (1.5 g) were heated together under reflux in pyridine (10 ml) for 24 hr. The mixture was stripped and the residue triturated with wet ether. Recrystallisation three times from ethanol/water gave 2-[3-(N-propyl-N-pyrid-2-ylamino) propylamino)-5-(6-methylpyrid-3-ylmethyl)pyrimid-4-one 0.9H2O, 1.45 g (62%) mp 83°-90° C. (softens).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04547506 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-433a6d3c77c24998bda1c6d64cb42f60 |
| Source note | uspto-grants-1985_10 |