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HRID464353

反应详情

EQUATION

反应方程式

HRID 464353 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(Cc2cnc(N[N+](=O)[O-])[nH]c2=O)cn1
HCID3018360

N-{4-Hydroxy-5-[(6-methylpyridin-3-yl)methyl]pyrimidin-2-yl}nitramide

C11H11N5O3

结构：NCCN(Cc1ccccc1)c1ccccn1
HCID19831051

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(Cc2cnc(NCCN(Cc3ccccc3)c3ccccn3)[nH]c2=O)cn1
HCID54180461

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

2-[N-(2-aminoethyl)-N-benzylamino]pyridine (0.95 g) and 2-nitroamino-5-(6-methylpyrid-3-ylmethyl)pyrimid-4-one (0.91 g) were heated together under reflux in pyridine (10 ml) for 20 hr. After stripping, the residue was triturated with ether and recrystallised from methanol to give 2-[2-(N-benzyl-N-pyrid-2-ylamino)ethylamino]-5-(6methylpyrid-3-ylmethyl) pyrimid-4-one, 1.02 g (68%) mp 178°-82° C.

WORKUP

后处理

  1. customthe residue was triturated with ether
  2. customrecrystallised from methanol