huagongshe.com
HRID464355

反应详情

EQUATION

反应方程式

HRID 464355 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(Cc2cnc(N[N+](=O)[O-])[nH]c2=O)cn1
HCID3018360

N-{4-Hydroxy-5-[(6-methylpyridin-3-yl)methyl]pyrimidin-2-yl}nitramide

C11H11N5O3

结构：NCCCN(Cc1ccccc1Cl)c1ccccn1
HCID20207332

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(Cc2cnc(NCCCN(Cc3ccccc3Cl)c3ccccn3)[nH]c2=O)cn1
HCID54092413

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

2-[N-(3-aminopropyl)-N-(2-chlorobenzyl)amino]pyridine (1 g) and 2-nitroamino-5-(6-methylpyrid-3-ylmethyl)pyrimid-4-one (0.78 g) were heated together under reflux in pyridine (10 ml) for 20 hr. After stripping, the residue was triturated with ether and recrystallised twice from ethanol/water to give 2-[3-[N-(2-chlorobenzyl)-N-pyrid-2-ylamino]propylamino]-5-(6-methylpyrid-3-ylmethyl)-pyrimid-4-one 0.4H2O, 0.34 g (20%) mp softens 94°-102° C. melts 120°-26° C.

WORKUP

后处理

  1. customthe residue was triturated with ether
  2. customrecrystallised twice from ethanol/water