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HCID 13373474、化合物 → 2-[3-(N-benzyl-N-pyrid-2-ylamino)propylamino]-5-pyrid-4-ylmethylpyrimid-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | HCID 13373474 | HCID 13373474 | — |
| 反応物 | 2-[N-(3-aminopropyl)-N-benzylamino)pyridine | HCID 20150364 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 2-[3-(N-benzyl-N-pyrid-2-ylamino)propylamino]-5-pyrid-4-ylmethylpyrimid-4-one | HCID 20262891 | — |
反応手順
2-[N-(3-aminopropyl)-N-benzylamino)pyridine (1.0 g) and 2-nitroamino-5-(pyrid-4-ylmethyl)pyrimid-4-one (0.68 g) were heated together under reflux in pyridine (2.5 ml) for 23 hr. After stripping the residue was twice crystallized from ethanol/water to give 2-[3-(N-benzyl-N-pyrid-2-ylamino)propylamino]-5-pyrid-4-ylmethylpyrimid-4-one 1.6 H2O, 0.86 g (68%) m.p. 87°-89° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04547506 |
| 出典データセット | uspto-grants-1985_10 |
| ORD ID | ord-7ed901a7345a4bd2ba1887c458807b33 |
| 出典メモ | uspto-grants-1985_10 |