Hydrochloric Acid → 1,5-Dichloro-3,3-dimethylpentan-2-one

Participants

Reaction Steps

A powerful stream of hydrogen chloride gas is passed from a cylinder into 476 g (3.25 mol) of 2-chloromethylene-3,3-dimethyltetrahydrofuran, while cooling with ice. The gas is absorbed completely, and the internal temperature rises to 30° C. When the reaction mixture is completely saturated with hydrogen chloride, it is subsequently stirred at room temperature for 2 hours. Excess hydrogen chloride is first removed under a water pump, and the mixture is then distilled under a good vacuum. 531 g (90% of theory) of 1,5-dichloro-3,3-dimethyl-2-pentanone of melting point 85°-90° C./0.3 mbar are obtained. ##STR31##

Provenance & Evidence