Cyclohexane → HCID 54510663, compound

HRID 464491Notes

Reaction equation

HRID 464491 reaction equation
C1CCCCC1.[NH:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1.[CH:13](=O)[CH2:14][CH:15]([CH3:17])[CH3:16]>O>[CH3:16][CH:15]([CH3:17])[CH:14]=[CH:13][N:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1

Participants

5

Reactant 3

HCID 8078CyclohexaneHCID 8083MorpholineHCID 115523-Methylbutanal

Product 1

HCID 54510663HCID 54510663, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
50 °C

Procedure

Into a 12 liter flask equipped with stirrer, Bidwell trap, thermometer, heating mantle, addition funnel and condenser is placed 2,200 ml of cyclohexane and 2,180 grams (25 moles) of morpholine. The resulting mixture is heated to 50° C. and 2,155 grams of isovaleraldehyde are added over a 1.5 hour period. An exotherm occurs and the solution begins to reflux. Additional heat is applied and the refluxing is continued until no additional water is collected in the Bidwell trap. The cyclohexane is then stripped off and the reaction product is distilled through a 1" stone packed column at total take-off yielding the following fractions:

Workup

  1. customInto a 12 liter flask equipped with stirrer
  2. temperatureBidwell trap, thermometer, heating
  3. additionmantle, addition funnel and condenser
  4. temperatureto reflux
  5. temperatureAdditional heat
  6. customis collected in the Bidwell trap
  7. distillationthe reaction product is distilled through a 1" stone
  8. customtake-off yielding the following fractions

Sources & evidence

ORD record
ord-68d3ee6271ef4e1483bceac50b386a83
Source dataset
uspto-grants-1985_10
Patent number
US04547594

Reaction notes

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