HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-Amino-1-cyclopropyl-5-nitroso-2,4(1H,3H)-pyrimidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-Amino-1-cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione | HCID 7131548 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Solvent | Water | HCID 962 | — |
| Product | 6-Amino-1-cyclopropyl-5-nitroso-2,4(1H,3H)-pyrimidinedione | HCID 54223493 | — |
Reaction Steps
31.7 g (0.19 mol) of 6-amino-1-cyclopropyl-2,4-(1H,3H)-pyrimidinedione (II) was suspended in 250 ml water. To this was added 45 ml of 5N HCl and 15 g of NaNO2 (0.22 mol) which was dissolved in water. The reaction mixture was stirred for 2 hours and after cooling, the red crystals were filtered off and washed with water. Yield 31.9 g (86%) (III) NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04548818 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-23f0ec4a203c41439a804afeacc0a235 |
| Source note | uspto-grants-1985_10 |