Acetone → HCID 54010919, compound

Participants

Reaction Steps

A mixture of 8 g (0.033 m) of the product of Example 8, 5.3 g (0.039 m) of N-methylmorpholine N-oxide, 4 ml of 2.5% osmium tetroxide in t-butanol, and 20 ml of acetone was stirred for four hours then extracted with ethylacetate. The organic solution was washed with brine, dried, and stripped to give 12 g of crude product which was purified by dry column chromatrography (silica gel, ethylacetate:hexane::1:1) to yield 5.8 g of the title compound as a white solid, M. 124°-6° C.

Provenance & Evidence