HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-((6-Methyl-3-pyridyl)methyl)-2-(nitroamino)-1H-pyrimidin-4-one → HCID 14397373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-((6-Methyl-3-pyridyl)methyl)-2-(nitroamino)-1H-pyrimidin-4-one | HCID 3018360 | — |
| Solvent | 1,3-Propanediamine | HCID 428 | — |
| Product | HCID 14397373 | HCID 14397373 | — |
Reaction Steps
1,3-Diaminopropane (60 ml) and 2-nitroamino-5-(6-methylpyrid-3-ylmethyl)-4-pyrimidone (5.22 g) were heated together under reflux for 2.5 hr. Excess amine was stripped off and the residue recrystallised from ethanol to give 2-(3-aminopropylamino)-5-(6-methylpyrid-3-ylmethyl)-4-pyrimidone, (4.3 g; 79%) m.p. 162°-164° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04548940 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-c57dea660ec44cf9885f1babc5627187 |
| Source note | uspto-grants-1985_10 |