5-(4-Chlorobenzyl)-2-methylthiopyrimid-4-one → HCID 53925041, compound

Participants

Reaction Steps

2-(3-Aminopropylamino)-3-chloropyridine (1 g) and 5-(4-chlorobenzyl)-2-methylthio-4-pyrimidone (1.3 g) were heated together under reflux in pyridine (20 ml) for 48 hr. The mixture was stripped and recrystallised from dimethyl formamide/ethanol/water to give 5-(4-chlorobenzyl)-2-[3-(3-chloropyrid-2-ylamino)propylamino]-4-pyrimidone 0.7H2O, (1.55 g; 76%) m.p. 180°-81° C.

Provenance & Evidence