4-Toluenesulfonyl chloride → 2,3-Dihydro-1-[(4-methylphenyl)sulfonyloximino]-3-phenyl-1H-indene

Participants

Reaction Steps

A solution of p-toluenesulfonyl chloride (102.2 g) in pyridine (140 ml) was added dropwise at 5°-10° to 2,3-dihydro-1-(hydroxyimino)-3-phenyl-1H-indene (60 g) in 270 ml pyridine. The reaction mixture was then stirred for 8 hours at room temperature, poured into ice-water to separate out the title compound, which was filtered, washed several times with water, then once with ether, and finally dried in air. Yield: 96.5 g; m.p. 123°-127°.

Provenance & Evidence