HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 1-(2,6-Dimethoxybenzoyl)-3-(6-Cyclohexylsulfonyl-3-Pyridinyl)Urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 2,6-Dimethoxybenzoyl isocyanate | HCID 13321994 | — |
| Reactant | 6-(Cyclohexylsulfonyl)pyridin-3-amine | HCID 20387355 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-(2,6-Dimethoxybenzoyl)-3-(6-Cyclohexylsulfonyl-3-Pyridinyl)Urea | HCID 20387354 | — |
Reaction Steps
2-Cyclohexylsulfonyl-5-aminopyridine (1.0 gram) and 2,6-dimethoxybenzoyl isocyanate (0.9 gram) were mixed in 50 ml. of DMF and stirred at room temperature overnight (about 18 hours). The reaction mixture was then poured into water and filtered to separate the product. It was crystallized from ethyl acetate-hexanes, yield 0.5 gram, m.p., 123°-125° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04173639 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-d774e13f129349a08e611c740d2ad94b |
| Source note | uspto-grants-1979_11 |