HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitromethane → HCID 54082890, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitromethane | HCID 6375 | — |
| Reactant | 1,1,3,3-Tetramethylguanidine | HCID 66460 | — |
| Reactant | Methyl 3-(4-methylphenyl)-2-propenoate | HCID 589472 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 54082890 | HCID 54082890 | — |
Reaction Steps
A mixture to 300 g of p-methylcinnamic acid, methyl ester, 500 g of nitromethane and 39 g of tetramethylguanidine is allowed to stir at room temperature for 72 hours. The solution is diluted with diethyl ether and (1 liter, 1 N) aqueous hydrochloric acid solution added. The organic layer is separated, dried over anhydrous magnesium sulfate, and evaporated to give 4-nitro-3-(4-methylphenyl) butanoic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04548947 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-8224e872398d4797b5f96db9535e17b7 |
| Source note | uspto-grants-1985_10 |