HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 23324910, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 54255244 | HCID 54255244 | — |
| Reactant | HCID 54405235 | HCID 54405235 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 23324910 | HCID 23324910 | — |
| Product | HCID 23324926 | HCID 23324926 | — |
Reaction Steps
A solution of 36.7 g of 3-(4-chlorophenyl)-5-oxo-2-pyrrolidinepropanoic acid methyl ester and β-(4-chlorophenyl)-5-oxo-2-pyrrolidinepropanoic acid methyl ester in aqueous sodium hydroxide (1 N, 130 ml) solution is heated to 60° C. for four hours. Excess aqueous hydrochloric acid (1 N, 140 ml) is added and solution is concentrated under reduced pressure to give β-(4-chlorophenyl)-5-oxo-2-pyrrolidinepropanoic acid and 3-(4-chlorophenyl)-5-oxo-2-pyrrolidinepropanoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04548947 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-4ba4e28073ca4916964985b7f4aba45f |
| Source note | uspto-grants-1985_10 |