HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 23324916, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 53908089 | HCID 53908089 | — |
| Reactant | 3-(3,4-Dichlorophenyl)-5-oxo-2-pyrrolidinepropanoic acid methyl ester | HCID 54079355 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 23324916 | HCID 23324916 | — |
| Product | HCID 23324918 | HCID 23324918 | — |
Reaction Steps
A solution of 34.1 g of 3-(3,4-dichlorophenyl)-5-oxo-2-pyrrolidinepropanoic acid methyl ester and β-(3,4-dichlorophenyl)-5-oxo-2-pyrrolidinepropanoic acid methyl ester in aqueous sodium hydroxide solution (1 N, 108 ml) is heated to 60° C. for four hours. Excess aqueous hydrochloric acid (1 N, 120 ml) is added and the solution is concentrated under reduced pressure to give β-(3,4-dichlorophenyl)-5-oxo-2-pyrrolidinepropanoic acid and 3-(3,4-dichlorophenyl)-5-oxo-2-pyrrolidinepropanoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04548947 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-03b2be34637d43b590b03fd4b6060888 |
| Source note | uspto-grants-1985_10 |