Methanol → 4-Methoxycinnamate methyl ester

HRID 464736ノート

反応式

HRID 464736 の反応式
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6]([CH:7]=[CH:8][C:9]([OH:11])=[O:10])=[CH:5][CH:4]=1.S(=O)(=O)(O)O.[CH3:19]O>>[CH3:19][O:10][C:9](=[O:11])[CH:8]=[CH:7][C:6]1[CH:12]=[CH:13][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1

参加物

4

反応物 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 132454-Methoxy cinnamic acid

生成物 1

HCID 928414-Methoxycinnamate methyl ester

実験手順

A suspension of 300 g of 4-methoxycinnamic acid (J. Chem. Soc., Chem. Comm., 355, (1978)) and 25 ml of concentrated sulfuric acid in 1.7 liters of methanol is heated to reflux for 96 hours. The solution is concentrated, cooled, and filtered to give as a white solid, 4-methoxycinnamic acid methyl ester, mp 85°-86° C.

後処理

  1. temperatureis heated
  2. temperatureto reflux for 96 hours
  3. concentrationThe solution is concentrated
  4. temperaturecooled
  5. filtrationfiltered

出典と根拠

ORDレコード
ord-cde8d7e643394330bc4208001dec3e3b
出典データセット
uspto-grants-1985_10
特許番号
US04548947

反応ノート

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