Sulfuric Acid → HCID 70482362, compound

Participants

Reaction Steps

2-(p-methoxyphenethyl)-5-(2,2-dimethyl-1,3-benzoxathiol-5-yl)hydroxymethylpyrrolidine acetate prepared according to Example 6.B. (1.0 g) is dissolved in a solution of 1 ml 50% aqueous sulfuric acid in 10 ml ethanol and the resulting precipitate harvested. The product is suspended in ethanol and filtered, air dried, and recrystallized from methanol/acetone to yield 2-(p-methoxyphenethyl)-5-(2,2-dimethyl-1,3-benzoxathiol-5-yl)hydroxymethylpyrrolidine bisulfate.

Provenance & Evidence