Water → HCID 20262667, compound

Participants

Reaction Conditions

Reaction Steps

A 376 g sample of 2,4-dimethyl-2-phenyl-4-pentenal (prepared via the method of U.S. Pat. No. 3,996,290) was added to 38 g of lithium aluminum hydride in 1200 ml of anhydrous ether over a 1 hr period with cooling to maintain 25° C. At the end of the addition, 76 g of water and 61 g of 10% aqueous sodium hydroxide were carefully added and the mixture was stirred for 2 hrs. The mixture was filtered, concentrated on a rotary evaporator and distilled, affording 370 g of 2,4-dimethyl-2-phenyl-4-penten-1-ol, (bp 125°-127°/0.5 mm Hg), in a 97% yield and a purity of 99%. Spectral data were in agreement with the assigned structure.

Provenance & Evidence