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HRID464833

反应详情

EQUATION

反应方程式

HRID 464833 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)CCl
HCID66052

1,1-Dimethylethyl chloroacetate

C6H11ClO2

结构：O=C(N[C@H]1COc2ccccc2NC1=O)OCc1ccccc1
HCID18599718

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)CN1C(=O)[C@@H](NC(=O)OCc2ccccc2)COc2ccccc21
HCID70045024

未命名化合物

收率 96.4%

PROCEDURE

实验过程

3(S)-Benzyloxycarbonylamino-2,3,4,5-tetrahydro-1,5-benzoxazepine-4-one (1.9 g) obtained in Example 14 is reacted with 1.1 g of tert-butyl chloroacetate in a manner similar to that of Example 4 to give 2.5 g of tert-butyl 3(S)-benzyloxycarbonylamino-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-5-acetate as a pale yellow oil.