反应详情

A mixture of 32.32 g of 2-[[[1-(phenylmethyl)-3-pyrrolidinyl]methyl]amino]ethanol, 330 ml of methanol and 3 g of 20% palladium on charcoal was shaken in an atmosphere of hydrogen at about 50 psi and at room temperature for 18 hours. The solvents were then removed at reduced pressure. The residue was distilled under vacuum, bp 129°-131° C. (1.5 mm) to give 11.43 g of 2-[(3-pyrrolidinylmethyl)amino]ethanol.

1. customThe solvents were then removed at reduced pressure
2. distillationThe residue was distilled under vacuum, bp 129°-131° C. (1.5 mm)