HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidin-1-ylmethyl-piperidine → 5,10-Dihydro-5-[[2-[(1-pyrrolidinyl)methyl]-1-piperidinyl]-acetyl]-11H-dibenzo[b,e][1,4]diazepin-11-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidin-1-ylmethyl-piperidine | HCID 2760541 | — |
| Reactant | 5-(chloroacetyl)-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one | HCID 10085419 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 5,10-Dihydro-5-[[2-[(1-pyrrolidinyl)methyl]-1-piperidinyl]-acetyl]-11H-dibenzo[b,e][1,4]diazepin-11-one | HCID 13578560 | — |
Reaction Steps
The title compound is prepared analogously to Example 2 from 5-(chloroacetyl)-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one and 2-[(1-pyrrolidinyl)methyl]piperidine to give colorless crystals, mp. 199°-201° C. (isopropanol/activated charcoal).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04550107 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-711934a3e9b749f5b2dcdd02faf2cc66 |
| Source note | uspto-grants-1985_10 |