huagongshe.com
HRID465079

反应详情

EQUATION

反应方程式

HRID 465079 的结构方程式

REACTANTS

反应物

2
结构：O=C1Nc2cccnc2N(C(=O)CCl)c2ccccc21
HCID120053

11-(Chloroacetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one

C14H10ClN3O2

结构：CN1CCN(C[C@@H]2CCCN2)CC1
HCID13275116

1-Methyl-4-{[(2S)-pyrrolidin-2-yl]methyl}piperazine

C10H21N3

PRODUCTS

生成物

1
结构：CN1CCN(C[C@@H]2CCCN2CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1
HCID13578578

未命名化合物

PROCEDURE

实验过程

The title compound is prepared analogously to Example 31 from 11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and (S)-(+)-2-[(4-methyl-1-piperazinyl) methyl]pyrrolidine to give colorless crystals, mp. 182°-185° C. (D) (from ethyl acetate/methanol 99:1 v/v); [α]D20 =-11.2° (ethanol).