反应详情

温度

130 °C

A mixture of 0.27 g of 2'-hydrazino-3,3'-bipyridine and 5 ml of triethyl orthoacetate was heated at 130° C. for 1.5 hours and the solvent removed. The residue was chromatographed on silica gel and eluted first with ethyl acetate:methanol (9:2), then with methanol to elute the product. This solid was recrystallized from methylene chloride-hexane giving the desired product as tan crystals, mp 112°-115° C.

1. customthe solvent removed
2. customThe residue was chromatographed on silica gel
3. washeluted first with ethyl acetate:methanol (9:2)
4. washwith methanol to elute the product
5. customThis solid was recrystallized from methylene chloride-hexane giving the desired product as tan crystals, mp 112°-115° C.