Beta-Alanine → HCID 20261959, compound

Participants

Reaction Steps

Amounts of 8.90 g of 2,4-bis(2,4-dichlorophenoxy)nitrobenzene, 5.35 g of β-alanine and 11.06 g of K2CO3 were added to 50 ml acetonitrile. The reaction mixture was refluxed for 5 days. After evaporating the solvent the residue was stirred with 150 ml of water and 100 ml of diethylether for 1 hour. The water phase was acidified with conc. hydrochloric acid and extracted with methylene chloride. After drying and evaporating the solvent the organic layer yielded the desired product as a yellow crystalline material; melting-point 115° C.; yield 2.64 g.

Provenance & Evidence